The gut is the front line
Whoever colonises the gut
first sets the course.
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Sites held by beneficial bacteria
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Pathogens turned away
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Villi fully secured
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hours after hatching
A chick hatches with an almost empty gut.The first bacteria to settle there shape how the gut lining develops, how the immune system matures and which pathogens can find a place to attach.
The idea is 50 years old.In 1973, Nurmi and Rantala showed that day-old chicks given gut bacteria from healthy adult hens resisted Salmonella colonisation. This became known as competitive exclusion.